Bit DNA Squeezer (BDNAS) : A Unique Technique for Dna Compression

Abstract

Data compression plays a vital role in analyzing, decreasing and transferring DNA sequences, hence escalating the creation of DNA compression techniques in order to store and transfer tremendous amount of genomic data. A fresh flow of interest in the development of novel algorithms and tools for storing and managing genomic sequences highlights the increasing demand for efficient methods for DNA compression. This is basically, the motivating force behind the development of high-performance compression tools designed specifically for genomic data. Most of the earlier DNA compression methods were essentially dictionary-based methods or statistical methods. Recently 2-bit coding methods have become prominent where the 4 nucleotide bases {A, C, G, T} in DNA sequences are assigned values 00, 01, 10 and 11 respectively. In this paper an attempt has been made to present an approach where a single bit (0 or 1) is assigned for each nucleotide base {A,C,G,T} in a DNA sequence depending on the count of each nucleotide. This proposed technique compresses large bytes of DNA sequences with the average compression ratio of approximately 1.4 bits per base.