Drug Prediction System Using Data Mining Techniques - A Survey

Authors

  • V. Jagadeesan  Research Scholar, Department of Computer Science, A.V.C. College (Autonomous), Mayiladuthurai, India
  • Dr. K. Palanivel  Research Supervisor, Department of Computer Science, A.V.C. College(Autonomous), Mayiladuthurai, India

DOI:

https://doi.org//10.32628/CSEIT183813

Keywords:

Drug Query System, Knowledge Discovery in Database, Supervised, Unsupervised and Semi-supervised

Abstract

The thriving Medical applications of Data mining in the fields of medicine and public health has led to the popularity of its use in Knowledge Discovery in Databases (KDD). Data mining has revealed novel Biomedical and Healthcare acquaintances for Clinical decision making that has great potential to improve the treatment quality of hospitals and increase the survival rate of patients. Drug Prediction is one of the applications where data mining tools are establishing the successful results. Data mining intends to endow with a systematic survey of current techniques of knowledge discovery in databases using data mining techniques that are in use in today’s medical research. To enable the drug retrieval and the breakthrough of hidden retrieval patterns from related databases, a study is made. Also, the use of data mining to discover such relationships as those between Supervised and Unsupervised are presented. This paper summarizes various machine learning algorithm on various data mining techniques in Learning strategies. It has also been targeted on contemporary research being done the usage of the Data mining strategies to beautify the retrieval manner. This research paper offers destiny developments of modern-day strategies of KDD, using data mining equipment for medicinal drug industry. It also confers huge troubles and demanding situations related to information mining and medication area in fashionable. The research discovered a developing quantity of records mining packages, such as evaluation of drugs names for higher fitness policy-making, detection of accurate effects with outbreaks and preventable from misclassified drug names

References

  1. E. Bressoet al., "Integrative relational machine-learning for understanding drug side-effect profiles", BMC Bioinf., vol. 14, Jun. 2013, Art.no. 207.
  2. T. Liu and R. B. Altman, "Relating essential proteins to drug side effects using canonical component analysis: A structure-based approach"J. Chem. Inf. Model., vol. 55, no. 7, pp. 1483_1494, 2015.
  3. D. S.Wishartet al., "DrugBank: A knowledgebase for drugs, drug actions and drug targets", Nucl. Acids Res., vol. 36, pp. D901_D906, Nov. 2008.
  4. J. Bowes et al., "Reducing safety-related drug attrition: The use of in vitro pharmacological profiling", Nature Rev. Drug Discovery, vol. 11, no. 12, pp. 909_922, 2012.
  5. X. Wang, B. Thijssen, and H. Yu, "Target essentiality and centrality characterize drug side effects", PLoSComput.Biol., vol. 9, no. 7, p. e1003119, 2013.
  6. M. Duran-Frigola and P. Aloy, "Analysis of chemical and biological features yields mechanistic insights into drug side effects", Chem. Biol., vol. 20, no. 4, pp. 594_603, 2013.
  7. T. Liu and R. B. Altman, "Relating essential proteins to drug side effects using canonical component analysis: A structure-based approach"J. Chem. Inf. Model., vol. 55, no. 7, pp. 1483_1494, 2015.
  8. S. Jamal, S. Goyal, A. Shanker, and A. Grover, "Predicting neurological adverse drug reactions based on biological, chemical and phenotypic properties of drugs using machine learning models"Sci. Rep., vol. 7, Apr. 2017, Art. no. 872.
  9. J. Scheiberet al., "Mapping adverse drug reactions in chemical space",J. Med. Chem., vol. 52, no. 9, pp. 3103_3107, 2009.
  10. Y. Yamanishi, M. Kotera, M. Kanehisa, and S. Goto, "Drug-target interaction prediction from chemical, genomic and pharmacological data in an integrated framework" Bioinformatics, vol. 26, no. 12, pp. i246_i254, 2010
  11. A. F. Fliri, W. T. Loging, P. F. Thadeio, and R. A. Volkmann, "Analysis of drug-induced effect patterns to link structure and side effects of medicines," Nature Chem. Biol., vol. 1, no. 7, 2005.
  12. J. Scheiberet al., "Gaining insight into off-target mediated effects of drug candidates with a comprehensive systems chemical biology analysis," J. Chem. Inf. Model., vol. 49, no. 2, 2009.
  13. F. Wang, P.Zhang, N. Cao, J. Hu, and R. Sorrentino, "Exploring the associations between drug side-effects and therapeutic indications,"J.Biomed.Inform.,vol. 51, Oct.2014.
  14. S. Mizutani, E. Pauwels, V. Stoven, S. Goto, and Y. Yamanishi, "Relating drug protein interaction network with drug sideeffects," Bioinformatics, vol. 28, no. 18, 2012.
  15. Y. Yamanishi, E. Pauwels, and M. Kotera, "Drug side-effect prediction based on the integration of chemical and biological spaces," J. Chem. Inf.Model., vol. 52, no. 12, 2012.
  16. M. Liu et al., "Determining molecular predictors of adverse drug reactions with causality analysis based on structure learning," J. Amer. Med. Inform.Assoc., vol. 21, no. 2, 2014.
  17. F. Cheng et al., "Adverse drug events: Database construction and in silicoprediction," J. Chem. Inf. Model., vol. 53, no. 4, pp. 744-752, 2013.
  18. W. Zhang, H. Zou, L. Luo, Q. Liu, W. Wu, and W. Xiao, "Predictingpotential side effects of drugs by recommender methods and ensemble learning," Neurocomputing, vol. 173, pp. 979-987, Jan. 2016.
  19. Y.-G. Chen, Y.-Y.Wang, and X.-M.Zhao, "A survey on computational approaches to predicting adverse drug reactions," Current Topics Med.Chem., vol. 16, no. 30, 2016.
  20. D. P. Williams and B. K. Park, "Idiosyncratic toxicity: The role of toxicophores and bioactivation," Drug Discovery Today, vol. 8, no. 22, pp. 1044-1050, 2003.

Downloads

Published

2018-11-30

Issue

Section

Research Articles

How to Cite

[1]
V. Jagadeesan, Dr. K. Palanivel, " Drug Prediction System Using Data Mining Techniques - A Survey, IInternational Journal of Scientific Research in Computer Science, Engineering and Information Technology(IJSRCSEIT), ISSN : 2456-3307, Volume 3, Issue 8, pp.32-43, November-December-2018. Available at doi : https://doi.org/10.32628/CSEIT183813