Synthesis and Characterization of Metal Oxide Nanocomposites; Application in Electrochemical Detection of Neurotramsmitter
Keywords:
Dopamine, Nanocomposites, Modified Carbon Paste Electrode, Cyclic voltammetry.Abstract
ZnO-NiO nanocomposite(NC) has been synthesized by co-precipitation method. This ZnO-NiO composite has been characterized by using, x-ray diffraction (XRD), scanning electron microscope, (SEM). The synthesized composite exhibited a good sensing property and applied for the electrochemical detection of a neurotransmitter, dopamine (DA). ZnO-NiO modified carbon paste electrode (MCPE) showed good catalytic property towards the oxidation of DA. The developed nanocomposite sensor offered high catalytic activity in sensing the dopamine MCPE application in the development of biosensors. The electrochemical responses of 5×10?5 M DA and recorded voltagramm at the potential range of -0.2 to 0.6 v vs. SCE in the 0.2 M phosphate buffer of pH 7.2 by Cyclovoltametric technique for both bare carbon paste electrode (BCPE) and MCPE. A good linearity has been observed between scan rate (v) and redox peak current for ZnO-NiO composite MCPE with correlation coefficients of R = 0.97811. These results indicated that electron transfer reaction is adsorption controlled. Therefore, ZnO-NiO nanocomposite could serve as an alternative material as sensor material for the electrochemical detection of dopamine.
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